Concomitant Asymptomatic Intracranial Atherosclerotic Stenosis Increase the 30-Day Risk of Stroke in Patients Undergoing Symptomatic Intracranial Atherosclerotic Stenosis Stenting
| Autor: | Bing-Wu Ma, Hua-Dong Zhou, Gui-Sheng Chen, Xiao-Jiang Jiang, Qingwu Yang, Lu-Xiang Chi, Xiong-Fei Zhao, Yan-Hui Du, Xiaohui Li, Xiao-Feng Yao, Jin Zhao, Jing-Cheng Li |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty China Time Factors medicine.medical_treatment 030204 cardiovascular system & hematology Asymptomatic Risk Assessment Severity of Illness Index 03 medical and health sciences 0302 clinical medicine Modified Rankin Scale Risk Factors Angioplasty Internal medicine medicine Odds Ratio Humans cardiovascular diseases Stroke Asymptomatic Diseases Retrospective Studies Chi-Square Distribution business.industry Rehabilitation Endovascular Procedures Stent Middle Aged medicine.disease Intracranial Arteriosclerosis Surgery Stenosis Logistic Models Treatment Outcome Concomitant Multivariate Analysis Cardiology Female Stents Neurology (clinical) medicine.symptom Cardiology and Cardiovascular Medicine business 030217 neurology & neurosurgery |
| Zdroj: | Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 27(2) |
| ISSN: | 1532-8511 |
| Popis: | In the Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) trial, 19.1% of ischemic strokes occurred out of the territory of previously symptomatic stenosis during the mean follow-up period of 23.4 months. However, it is unknown how many ischemic strokes were due to a previously asymptomatic intracranial atherosclerotic stenosis (ICAS). The objective of this study was to investigate whether the concomitant asymptomatic ICAS influences the outcome of patients undergoing symptomatic ICAS stenting.We retrospectively reviewed 576 consecutive patients with nondisabling ischemic stroke (modified Rankin scale score of ≤3) who were treated with symptomatic ICAS (≥70% stenosis) stenting with or without concomitant asymptomatic ICAS. The baseline characteristics and the 30-day primary end points (stroke or death after stenting) were compared by bivariate and multivariable logistic analyses.The 30-day rate of primary end points was 5.2%, which was higher in patients with concomitant asymptomatic ICAS (≥50% stenosis) than in those without asymptomatic ICAS (no stenosis or50% stenosis) (8.9% versus 3.8%, P = .014). In patients with concomitant asymptomatic ICAS, 25% of ischemic strokes occurred out of the territory of the stented artery, whereas in patients without asymptomatic ICAS, no ischemic stroke occurred out of the territory of the stented artery. Multivariable analysis showed that concomitant asymptomatic ICAS was an independent risk factor for 30-day stroke (odds ratio = 2.37, 95% confidence interval, 1.14-5.63; P = .023).Concomitant asymptomatic ICAS (≥50% stenosis) might increase the 30-day risk of stroke in patients undergoing symptomatic ICAS stenting. |
| Databáze: | OpenAIRE |
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