Fever induced in marine arthropods by prostaglandin E1

Autor: William W. Reynolds, M. E. Casterlin
Rok vydání: 1979
Předmět:
Zdroj: Life Sciences. 25:1601-1603
ISSN: 0024-3205
DOI: 10.1016/0024-3205(79)90443-0
Popis: Injections of prostaglandin E1 into the haemocoel of the marine arthropods Limulus polyphemus , Homarus americanus and Penaeus duorarum induced a behaviorally mediated fever (increase in preferred temperature, resulting in increased body temperature). The finding that PGE1 is pyorgenic to arthropods as well as to mammals suggests that arthropods can be used as simple experimental models for further investigations of the neuropharmacological role of prostaglandins in fever.
Databáze: OpenAIRE