Fever induced in marine arthropods by prostaglandin E1
Autor: | William W. Reynolds, M. E. Casterlin |
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Rok vydání: | 1979 |
Předmět: |
medicine.medical_specialty
Fever medicine.medical_treatment Zoology General Biochemistry Genetics and Molecular Biology Increased body temperature chemistry.chemical_compound Species Specificity stomatognathic system Decapoda Internal medicine Horseshoe Crabs medicine Animals Penaeus General Pharmacology Toxicology and Pharmaceutics Prostaglandin E1 Arthropods Homarus biology Prostaglandins E General Medicine biology.organism_classification Nephropidae Horseshoe crab Endocrinology chemistry Limulus lipids (amino acids peptides and proteins) Prostaglandin E |
Zdroj: | Life Sciences. 25:1601-1603 |
ISSN: | 0024-3205 |
DOI: | 10.1016/0024-3205(79)90443-0 |
Popis: | Injections of prostaglandin E1 into the haemocoel of the marine arthropods Limulus polyphemus , Homarus americanus and Penaeus duorarum induced a behaviorally mediated fever (increase in preferred temperature, resulting in increased body temperature). The finding that PGE1 is pyorgenic to arthropods as well as to mammals suggests that arthropods can be used as simple experimental models for further investigations of the neuropharmacological role of prostaglandins in fever. |
Databáze: | OpenAIRE |
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