Abdominal Obesity as a Predictive Factor of Nonalcoholic Fatty Liver Disease Assessed by Ultrasonography and Transient Elastography in Polycystic Ovary Syndrome and Healthy Women

Autor: Abhasnee Sobhonslidsuk, Sith Phongkitkarun, Kwannapa Promson, Sakda Arj-Ong Vallibhakara, Areepan Sophonsritsuk, Orawin Vallibhakara, Siriluk Tantanavipas
Rok vydání: 2019
Předmět:
Adult
medicine.medical_specialty
Article Subject
lcsh:Medicine
030209 endocrinology & metabolism
Gastroenterology
General Biochemistry
Genetics and Molecular Biology
Young Adult
03 medical and health sciences
0302 clinical medicine
Insulin resistance
Non-alcoholic Fatty Liver Disease
Internal medicine
Nonalcoholic fatty liver disease
Humans
Medicine
Abdominal obesity
Ultrasonography
General Immunology and Microbiology
business.industry
lcsh:R
Fatty liver
nutritional and metabolic diseases
General Medicine
Odds ratio
Prognosis
medicine.disease
Polycystic ovary
Obesity
Abdominal
Elasticity Imaging Techniques
Women's Health
Female
030211 gastroenterology & hepatology
Insulin Resistance
Waist Circumference
medicine.symptom
Steatosis
business
Transient elastography
Polycystic Ovary Syndrome
Research Article
Zdroj: BioMed Research International
BioMed Research International, Vol 2019 (2019)
ISSN: 2314-6141
2314-6133
Popis: Polycystic ovary syndrome (PCOS) and nonalcoholic fatty liver (NAFLD) share similar clinical presentations including obesity, insulin resistance (IR), and metabolic abnormality. The predictive factors of NAFLD in women with PCOS and specifically in Asian women are not well established. Associated factors for NAFLD assessed by ultrasound (US) among a group of PCOS and healthy women were determined and diagnostic accuracy between US and transient elastography (TE) for NAFLD was compared and correlated. Sixty-three women with ages ranging from 20 to 40 years participated in the present cross-sectional study. Forty-two women with PCOS as diagnosed by the Rotterdam criteria and 21 healthy women were recruited into the study. Women with underlying hepatic diseases and history of alcohol consumption >20 g/day were excluded. Biochemical and hormonal testing, anthropometrics, liver US, and TE were assessed. Waist circumference (WC) greater than 80 cm was the only predictive factor for NAFLD as assessed by US in the whole group (adjusted odds ratio [aOR] 5.49, 95% confidence interval [CI]: 1.85–16.26, p p p
Databáze: OpenAIRE
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