Neutralising antibodies against the transmembrane protein of feline leukaemia virus (FeLV)

Autor:	Reinhard Kurth, Joachim Denner, Uwe Fiebig, Stefan Langhammer
Rok vydání:	2005
Předmět:	Male viruses Blotting Western Antibody Affinity Antibodies Viral Homology (biology) Virus Epitope law.invention Epitopes Viral Envelope Proteins Neutralization Tests law hemic and lymphatic diseases Animals Cloning Molecular Rats Wistar Fluorescent Antibody Technique Indirect Antigens Viral General Veterinary General Immunology and Microbiology biology Reverse Transcriptase Polymerase Chain Reaction Goats Leukemia Virus Feline Public Health Environmental and Occupational Health Membrane Proteins virus diseases biology.organism_classification Virology Molecular biology Transmembrane protein Rats Retroviridae Infectious Diseases Epitope mapping Lentivirus HIV-1 biology.protein Recombinant DNA Molecular Medicine Electrophoresis Polyacrylamide Gel Antibody Epitope Mapping
Zdroj:	Vaccine. 23:3341-3348
ISSN:	0264-410X
Popis:	Neutralising antibodies specific for feline leukaemia virus (FeLV) were induced by immunisation with recombinant FeLV transmembrane envelope protein p15E. Epitope mapping revealed two epitopes located in similar regions to those previously identified for the porcine endogenous retrovirus (PERV). One of the epitopes has partial homology and both are located in regions corresponding to epitopes recognised by neutralising antibodies in patients infected with HIV-1.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dc19abcdcd31d0fee3e1e6a021ca196 https://doi.org/10.1016/j.vaccine.2005.01.091 Zobrazit plný text záznamu Full Text from ScienceDirect