First-order visual interneurons distribute distinct contrast and luminance information across ON and OFF pathways to achieve stable behavior
| Autor: | Maria Ioannidou, Marion Silies, Burak Gür, Carlotta Martelli, Madhura D Ketkar, Sebastian Molina-Obando |
|---|---|
| Rok vydání: | 2022 |
| Předmět: |
Computer science
Computation media_common.quotation_subject Motion Perception Adaptation (eye) ENCODE Luminance General Biochemistry Genetics and Molecular Biology Contrast Sensitivity Motion Interneurons Perception Animals Contrast (vision) Visual Pathways Computer vision Vision Ocular media_common General Immunology and Microbiology business.industry Visually guided General Neuroscience General Medicine First order Drosophila Artificial intelligence business Photic Stimulation |
| Zdroj: | eLife. 11 |
| ISSN: | 2050-084X |
| Popis: | The accurate processing of contrast is the basis for all visually guided behaviors. Visual scenes with rapidly changing illumination challenge contrast computation because photoreceptor adaptation is not fast enough to compensate for such changes. Yet, human perception of contrast is stable even when the visual environment is quickly changing, suggesting rapid post receptor luminance gain control. Similarly, in the fruit fly Drosophila, such gain control leads to luminance invariant behavior for moving OFF stimuli. Here, we show that behavioral responses to moving ON stimuli also utilize a luminance gain, and that ON-motion guided behavior depends on inputs from three first-order interneurons L1, L2, and L3. Each of these neurons encodes contrast and luminance differently and distributes information asymmetrically across both ON and OFF contrast-selective pathways. Behavioral responses to both ON and OFF stimuli rely on a luminance-based correction provided by L1 and L3, wherein L1 supports contrast computation linearly, and L3 non-linearly amplifies dim stimuli. Therefore, L1, L2, and L3 are not specific inputs to ON and OFF pathways but the lamina serves as a separate processing layer that distributes distinct luminance and contrast information across ON and OFF pathways to support behavior in varying conditions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|