European Prospective Investigation into Cancer and Nutrition (EPIC): Study populations and data collection
| Autor: | Göran Hallmans, Nicholas E. Day, Kim Overvad, Kelly J. Hunt, Pietro Ferrari, Antonia Trichopoulou, Françoise Clavel-Chapelon, Elio Riboli, Eiliv Lund, Timothy J. Key, Petra H.M. Peeters, Nadia Slimani, Teresa Norat, R. Saracci, Aurelio Barricarte, Rudolf Kaaks, Jürgen Wahrendorf, Jérôme Vignat, Domenico Palli, Heiner Boeing, Corinne Casagrande, Michael T. Fahey, Göran Berglund, H. B. Bueno-De-Mesquita, Charrondière Ur, Carlos A. González, Anne C. M. Thiébaut, Bertrand Hémon, Dagrun Engeset, Paolo Vineis, Anne Tjønneland, Dimitrios Trichopoulos |
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| Jazyk: | angličtina |
| Rok vydání: | 2002 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty MEDLINE Medicine (miscellaneous) biological samples Diet Surveys chronic diseases Environmental health Neoplasms Surveys and Questionnaires medicine cohort study cancer Humans Nutritional Physiological Phenomena Prospective Studies Registries Prospective cohort study Life Style Aged Nutrition and Dietetics anthropometry Anthropometry business.industry Public Health Environmental and Occupational Health Cancer Middle Aged medicine.disease European Prospective Investigation into Cancer and Nutrition EPIC study Europe nutrition Population Surveillance Cohort Female business Cohort study |
| Zdroj: | Riboli, E, Hunt, K J, Slimani, N, Ferrari, P, Norat, T, Fahey, M, Charrondieère, U R, Hémon, B, Casagrande, C, Vignat, J, Overvad, K, Tjønneland, A, Clavel-Chapelon, F, Thiébaut, A, Wahrendorf, J, Boeing, H, Trichopoulos, D, Trichopoulou, A, Vineis, P, Palli, D, Bueno-de-Mesquita, H B, Peeters, P H M, Lund, E, Engeset, D, Gonzalez, C A, Barricarte, A, Berglund, G, Hallmans, G, Day, N E, Key, T J, Kaaks, R & Saracci, R 2002, ' European Prospective Investigation into Cancer and Nutrition (EPIC): study populations and data collection ', Public Health Nutrition, vol. 5, no. 6b, pp. 1113-1124 . Aarhus University |
| ISSN: | 1368-9800 |
| Popis: | The European Prospective Investigation into Cancer and Nutrition (EPIC) is an ongoing multi-centre prospective cohort study designed to investigate the relationship between nutrition and cancer, with the potential for studying other diseases as well. The study currently includes 519 978 participants (366 521 women and 153 457 men, mostly aged 35–70 years) in 23 centres located in 10 European countries, to be followed for cancer incidence and cause-specific mortality for several decades. At enrolment, which took place between 1992 and 2000 at each of the different centres, information was collected through a non-dietary questionnaire on lifestyle variables and through a dietary questionnaire addressing usual diet. Anthropometric measurements were performed and blood samples taken, from which plasma, serum, red cells and buffy coat fractions were separated and aliquoted for long-term storage, mostly in liquid nitrogen. To calibrate dietary measurements, a standardised, computer-assisted 24-hour dietary recall was implemented at each centre on stratified random samples of the participants, for a total of 36 900 subjects. EPIC represents the largest single resource available today world-wide for prospective investigations on the aetiology of cancers (and other diseases) that can integrate questionnaire data on lifestyle and diet, biomarkers of diet and of endogenous metabolism (e.g. hormones and growth factors) and genetic polymorphisms. First results of case–control studies nested within the cohort are expected early in 2003. The present paper provides a description of the EPIC study, with the aim of simplifying reference to it in future papers reporting substantive or methodological studies carried out in the EPIC cohort. |
| Databáze: | OpenAIRE |
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