Synthesis and antiaggregant properties of Stabilized analogues of polyunsaturated fatty acid metabolites

Autor:	Tony Verbeuren, Ali Hachem, Yves Rolland, P. Roussel, Chiara Cerletti, René Grée, Eric Menager, Yves Le Floc'h, Serge Simonet, Danielle Grée
Rok vydání:	2002
Předmět:	Ketone Platelet Aggregation Platelet aggregation Carboxylic acid Clinical Biochemistry Pharmaceutical Science Biochemistry Chemical synthesis Drug Discovery Animals Humans Organic chemistry Platelet Molecular Biology Cells Cultured chemistry.chemical_classification Organic Chemistry General Medicine In vitro chemistry Fatty Acids Unsaturated Molecular Medicine Rabbits Aliphatic compound Platelet Aggregation Inhibitors Polyunsaturated fatty acid
Zdroj:	Bioorganic & Medicinal Chemistry Letters. 12:2511-2514
ISSN:	0960-894X
DOI:	10.1016/s0960-894x(02)00507-3
Popis:	New aromatic and heteroaromatic analogues of polyunsaturated fatty acid metabolites have been prepared using short and versatile strategies. Preliminary studies of their activity as inhibitors of platelet aggregation are reported.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db1db121f6ee67ca73dd36b0096a2ad https://doi.org/10.1016/s0960-894x(02)00507-3 Zobrazit plný text záznamu Full Text from ScienceDirect