Endometrial morphology in asymptomatic postmenopausal women
| Autor: | David F. Archer, Edmond A. Dowling, Frederick Cone, George W. Creasy, Michael E. Kafrissen, Kathleen McIntyre-Seltman, Walter W. Wilborn |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Adult
medicine.medical_specialty Biopsy Endometrium Asymptomatic Atypia Carcinoma Medicine Humans Prospective Studies Aged Ultrasonography Gynecology Uterine Diseases medicine.diagnostic_test business.industry Endometrial cancer Obstetrics and Gynecology Middle Aged medicine.disease Menopause medicine.anatomical_structure Endometrial Hyperplasia Uterine Neoplasms Female medicine.symptom business Endometrial biopsy |
| Zdroj: | American journal of obstetrics and gynecology. 165(2) |
| ISSN: | 0002-9378 |
| Popis: | Few data are available regarding endometrial histologic features in asymptomatic perimenopausal and postmenopausal women. This study encompasses endometrial biopsy specimens obtained from 801 such women before enrollment in a multicenter study of estrogen-progestin replacement. One endometrial cancer was found (0.13%); four additional biopsy specimens showed atypia (total 0.63%). The endometrium was atrophic in 373 (46.9%), proliferative in 133 (16.7%), secretory in 54 (6.8%), and hyperplastic in 41 (5.2%). Insufficient tissue for diagnosis was obtained in 195 (24.5%). We conclude that the yield for neoplasia is so low that screening endometrial biopsy is not justified in asymptomatic perimenopausal and postmenopausal women. |
| Databáze: | OpenAIRE |
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