Primary Ovarian Choriocarcinoma: Rare Entity
| Autor: | Shimelis Fantu Gebresilasie, Natnael Alemayehu Abebe, Mequanent Tariku Adow |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Chemotherapy
medicine.medical_specialty endocrine system business.industry medicine.drug_class medicine.medical_treatment Choriocarcinoma Obstetrics and Gynecology Case Report Gynecology and obstetrics medicine.disease Adnexal mass Ovarian Choriocarcinoma Regimen Laparotomy embryonic structures medicine RG1-991 Radiology Gonadotropin business Etoposide medicine.drug |
| Zdroj: | Case Reports in Obstetrics and Gynecology, Vol 2021 (2021) Case Reports in Obstetrics and Gynecology |
| ISSN: | 2090-6692 2090-6684 |
| Popis: | Background. Primary pure ovarian choriocarcinoma is a rare aggressive tumor which can be nongestational arising from germ cells or gestational origin. Preoperative diagnosis of extrauterine choriocarcinoma is challenging due to nonspecific clinical presentation. Case Presentation. This article reports primary ovarian choriocarcinoma, likely gestational in a 25-year-old para 2 woman presenting with lower abdominal pain and swelling of two-week duration. Diagnosis was suspected by serum beta-human chorionic gonadotropin and confirmed histologically after surgery. Postoperatively, she was managed with multiple courses of chemotherapy using a bleomycin, etoposide, and cisplatin regimen, and the treatment was effective. Conclusion. In patients with adnexal mass presenting with nonspecific symptoms especially with high Doppler blood flow of the mass on ultrasound evaluation, serum beta-human chorionic gonadotropin determination is recommended before laparotomy. In setups where the genomic test is not available, histological and clinical effort to differentiate gestational versus nongestational choriocarcinoma is useful for specific management decision. |
| Databáze: | OpenAIRE |
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