ETS-related gene is a novel prognostic factor in childhood acute lymphoblastic leukemia
| Autor: | Hai‑Zhao Zhao, Ming Jia, Ze‑Bin Luo, Jingying Zhang, Sisi Li, Xiao‑Ping Guo, Yong‑Min Tang, Xiao‑Jun Xu |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Oncology
Cancer Research medicine.medical_specialty genetic structures business.industry Cancer Articles medicine.disease Molecular medicine 03 medical and health sciences Leukemia 0302 clinical medicine medicine.anatomical_structure Immunophenotyping 030220 oncology & carcinogenesis Internal medicine White blood cell medicine sense organs Bone marrow business Childhood Acute Lymphoblastic Leukemia Erg 030215 immunology |
| Zdroj: | Oncology Letters. 13:455-462 |
| ISSN: | 1792-1082 1792-1074 |
| DOI: | 10.3892/ol.2016.5397 |
| Popis: | The ETS-related gene (ERG) has been demonstrated to be associated with overall survival in cytogenetically normal acute myeloid leukemia and acute T cell-lymphoblastic leukemia (T-ALL) in adult patients. However, there are no data available regarding the impact of ERG expression on childhood ALL. In the present study, ERG expression levels were analyzed in bone marrow samples from 119 ALL pediatric patients. ALL patients demonstrated higher ERG expression compared with the controls (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|