The quantitative carbohydrate ingestion ratio for extensive skeletal muscle uptake in 18F-FDG PET/computed tomography
| Autor: | Qin Yue, Chunmei Wang, Zhongyi Yang, Herong Pan, Yingying Zheng, Ying Qiao, Huiyu Yuan, Jing Xue, Yongxia Li, Yingjian Zhang |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Multivariate analysis Visual interpretation Computed tomography Gastroenterology 18f fdg pet Fluorodeoxyglucose F18 Internal medicine Positron Emission Tomography Computed Tomography Dietary Carbohydrates Medicine Ingestion Humans Radiology Nuclear Medicine and imaging Total energy Muscle Skeletal medicine.diagnostic_test business.industry Skeletal muscle Biological Transport General Medicine Carbohydrate Middle Aged medicine.anatomical_structure Multivariate Analysis Female business |
| Zdroj: | Nuclear medicine communications. 40(9) |
| ISSN: | 1473-5628 |
| Popis: | OBJECTIVES Extensive skeletal muscle accumulation (ESMA) of F-FDG adversely affects the visual interpretation of F-FDG PET/computed tomography (CT) images. We mainly investigated factors related to ESMA that are based on food compositions. METHODS From January 2018 to June 2018, a total of 5554 patients underwent F-FDG PET/CT imaging with at least a 4-hour fast. Among them, 49 patients who exhibiting ESMA and 50 sex-matched and age-matched patients without ESMA were included in the study. The following factors were analysed: BMI, plasma glucose, gastric residue, the total energy of food the patient had before F-FDG injection and the percentages of the food ingredients. Multivariate analysis was performed to evaluate related risk factors between two groups. RESULTS In brief, 49 cases and 50 controls were identified. The BMI, gross energy, gross energy of protein, gross energy of carbohydrate and proportion of protein of case group were not significantly different from that of the controls (P ≥ 0.05). The plasma glucose was significantly higher in the case group than in the control group (P = 0.002). The positivity of gastric food residue would more easily demonstrate ESMA than those without gastric food residue (P < 0.0001). The fasting time before scan, gross energy of fat, proportion of fat and proportion of carbohydrate in case group were significantly different with control group. After multivariate analysis, fasting time, gastric food residue and proportion of carbohydrate were investigated as independent risk factors. CONCLUSION To avoid ESMA, patients should take a lower proportion of carbohydrate before receiving an F-FDG administration. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|