A complicated path to the CRMO diagnosis - case of a 9 year old girl whose story comes full circle
| Autor: | Joanna Świdrowska-Jaros, Elżbieta Smolewska |
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| Rok vydání: | 2018 |
| Předmět: |
Pediatrics
medicine.medical_specialty lcsh:Diseases of the musculoskeletal system Bone disease Biopsy Bone Neoplasms Case Report Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Rare Diseases Rheumatology Pathognomonic Bone Marrow Musculoskeletal Pain medicine Humans Orthopedics and Sports Medicine Bone pain Child Radionuclide Imaging 030203 arthritis & rheumatology 030222 orthopedics Arthritis Infectious medicine.diagnostic_test Tibia business.industry Osteomyelitis Chronic recurrent multifocal osteomyelitis medicine.disease Magnetic Resonance Imaging Orthopedic surgery Female Differential diagnosis medicine.symptom lcsh:RC925-935 business Tomography X-Ray Computed |
| Zdroj: | BMC Musculoskeletal Disorders BMC Musculoskeletal Disorders, Vol 20, Iss 1, Pp 1-7 (2019) |
| ISSN: | 1471-2474 |
| Popis: | Background Chronic recurrent multifocal osteomyelitis (CRMO) is a rare idiopathic autoinflammatory bone disease that mostly affects children and adolescents. It is a diagnosis of exclusions since no clinical signs and symptoms are pathognomonic. Radiological tests are often essential, but bone biopsy may be needed in unclear cases. Case presentation A 9-year-old Caucasian girl with a history of bone pain. The data from the history and results of laboratory tests suggested osteomyelitis, but no adequate response to the treatment was observed. A number of imaging tests did not confirm the diagnosis, therefore a bone biopsy was necessary. Conclusions Differential diagnosis of CRMO is challenging and it is based on exclusions. Since it might be misdiagnosed or mistreated, bone biopsy should be considered in patients reporting bone pain who are unresponsive to treatment. |
| Databáze: | OpenAIRE |
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