Efficient estimation of allelic and genotypic proportions for electrophoretic loci

Autor:	C. A. Robertson, R. W. Marks
Rok vydání:	1983
Předmět:	Genetics fungi food and beverages Estimator General Medicine Biology Electrophoresis Plant biochemistry Genotype Allele Agronomy and Crop Science Allele frequency Biotechnology
Zdroj:	Theoretical and Applied Genetics. 65:197-200
ISSN:	1432-2242 0040-5752
DOI:	10.1007/bf00308065
Popis:	The efficiency of estimating allelic and genotypic frequencies at allozyme loci can often be increased by running more than one individual simultaneously in each sample slot in a gel. Increased precision in estimating allelic frequencies is always possible if Hardy-Weinberg proportions can be assumed. However, if Hardy-Weinberg cannot be assumed, estimates of both allelic and genotypic frequencies can be improved for loci with hybrid dimers, but not for loci without them. The efficiency of all estimators depends jointly on allele frequencies and the number of individuals run simultaneously.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8f7a4942b5f65feb0cca01d69ce028 https://doi.org/10.1007/bf00308065 Zobrazit plný text záznamu Full text from SpringerLink