Gephyrin: does splicing affect its function?

Autor:	Bertram Schmitt, Taslimarif Saiyed, Heinrich Betz, Ingo Paarmann
Rok vydání:	2006
Předmět:	Neurons Gephyrin Alternative splicing Membrane Proteins Exons Biology Biochemistry Cell biology Alternative Splicing Protein structure RNA splicing biology.protein Animals Humans Carrier Proteins Collybistin Gene Glycine receptor Ion channel
Zdroj:	Biochemical Society Transactions. 34:45-47
ISSN:	1470-8752 0300-5127
DOI:	10.1042/bst0340045
Popis:	Gephyrin is a protein involved in both synaptic anchoring of inhibitory ligand-gated ion channels and molybdenum cofactor synthesis. Substantial progress has been made in understanding its gene and protein structures. Furthermore, numerous binding partners of gephyrin have been identified. The mechanisms by which these interactions occur are unclear at present. Alternative splicing has been proposed to contribute to gephyrin's functional diversity within single cells as well as in different cell types and tissues.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8e03463fdcfa77160670535c91c7dc https://doi.org/10.1042/bst0340045 Zobrazit plný text záznamu