Effect of photodynamic therapy for the treatment of halitosis in adolescents - a controlled, microbiological, clinical trial
| Autor: | Cristiane Miranda França, Renato Araujo Prates, Larissa Costa Santos, Rubia Lopes Garcia, Raquel Agnelli Mesquita Ferrari, Ana Carolina Costa da Mota, Marcela Leticia Leal Gonçalves, Alessandro Melo Deana, Sandra Kalil Bussadori, Kristianne Porta Santos Fernandes |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Adolescent medicine.medical_treatment General Physics and Astronomy Dentistry Photodynamic therapy General Biochemistry Genetics and Molecular Biology Young Adult 03 medical and health sciences 0302 clinical medicine Tongue Statistical significance Humans Medicine General Materials Science Young adult Child Sulfur Compounds business.industry Significant difference General Engineering Liter Halitosis 030206 dentistry General Chemistry Clinical trial medicine.anatomical_structure Photochemotherapy 030220 oncology & carcinogenesis Female Analysis of variance business |
| Zdroj: | Journal of Biophotonics. 9:1337-1343 |
| ISSN: | 1864-063X |
| DOI: | 10.1002/jbio.201600067 |
| Popis: | Halitosis can exert a negative influence on the social relations of adolescents and affect one's self-image. The aim of this study was to evaluate the clinical and microbiological effect of antimicrobial photodynamic therapy (aPDT) on halitosis in adolescents. Forty-six individuals aged 12 to 19 years were randomly allocated: Group 1 - treatment with photodynamic therapy; Group 2 - treatment with a tongue scraper and Group 3 - treatment with a tongue scraper and photodynamic therapy. The count of bacterial colony-forming units per milliliter was used for the microbiological analysis. Statistical analysis involved the Kruskal-Wallis test followed by the Student-Newman-Keuls test. ANOVA was used for the determination of colony-forming units after treatment. The level of significance for all statistical tests was 5% (p < 0.05). After treatment, a statistically significant reduction in total volatile sulfur compounds was found in all groups (p < 0.001), with the largest reduction (median: 0) found in Group 3 (tongue scraper and photodynamic therapy). Moreover, a statistically significant difference was found between treatment with aPDT and a tongue scraper alone (p < 0.001). The present findings demonstrate an option for the treatment of halitosis in adolescents, with an immediate effect and without the mechanical aggression to the toungue. Clinical Trials: NCT02007993. |
| Databáze: | OpenAIRE |
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