Urea reduction ratio that considers effects of ultrafiltration and intradialytic urea generation
| Autor: | Yuk Lun Cheng, Alex W.Y. Yu, Ka Foon Chau, Koon Shing Choi, Chun Sang Li, Kwan Keung Wong, Chee Unn Yung |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.medical_treatment Urea reduction ratio Plasma urea Body weight Dialysis patients Surgery Blood Urea Nitrogen Ultrafiltration (renal) chemistry.chemical_compound Animal science chemistry Nephrology Renal Dialysis medicine Urea Humans Hemodialysis Hemofiltration business Dialysis Mathematics |
| Zdroj: | American journal of kidney diseases : the official journal of the National Kidney Foundation. 37(3) |
| ISSN: | 1523-6838 |
| Popis: | We modified the urea reduction ratio (URR) equation to correct the effects of ultrafiltration and intradialytic urea generation on the delivered dose of hemodialysis: mURR = [1 - (R/(1 + 2 * UF/BW)) + 0.01 * t] × 100% where mURR is modified URR, R is postdialysis plasma urea nitrogen (PUN) to predialysis PUN ratio, UF is ultrafiltrate volume in liters, BW is postdialysis body weight in kilograms, and t is dialysis session length in hours. The equation was validated against 145 hemodialysis treatments on 33 stable maintenance dialysis patients. The mURR values obtained closely predicted single-pool Kt/V (spKt/V) values. In contrast to conventional URR, the range of spKt/V values at each mURR value is narrow over a wide range of UF, t, and R values. Based on the mURR equation, mURR values of 64%, 70%, and 76% are mathematically equivalent to spKt/V levels of 1.0, 1.2, and 1.4, respectively. This equation can be a useful bedside tool to quantify hemodialysis dose. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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