Novel crystal timing calibration method based on total variation
| Autor: | Xingjian Yu, Takashi Isobe, Huafeng Liu, Mitsuo Watanabe |
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| Rok vydání: | 2016 |
| Předmět: |
Point source
Computer science 02 engineering and technology 030218 nuclear medicine & medical imaging Crystal 03 medical and health sciences 0302 clinical medicine Robustness (computer science) Image Interpretation Computer-Assisted 0202 electrical engineering electronic engineering information engineering Humans Radiology Nuclear Medicine and imaging Simulation Computer memory Signal processing Radiological and Ultrasound Technology Phantoms Imaging Brain Signal Processing Computer-Assisted Models Theoretical Full width at half maximum Positron-Emission Tomography Calibration 020201 artificial intelligence & image processing Algorithm Algorithms Linear equation |
| Zdroj: | Physics in Medicine and Biology. 61:7833-7847 |
| ISSN: | 1361-6560 0031-9155 |
| DOI: | 10.1088/0031-9155/61/22/7833 |
| Popis: | A novel crystal timing calibration method based on total variation (TV), abbreviated as 'TV merge', has been developed for a high-resolution positron emission tomography (PET) system. The proposed method was developed for a system with a large number of crystals, it can provide timing calibration at the crystal level. In the proposed method, the timing calibration process was formulated as a linear problem. To robustly optimize the timing resolution, a TV constraint was added to the linear equation. Moreover, to solve the computer memory problem associated with the calculation of the timing calibration factors for systems with a large number of crystals, the merge component was used for obtaining the crystal level timing calibration values. Compared with other conventional methods, the data measured from a standard cylindrical phantom filled with a radioisotope solution was sufficient for performing a high-precision crystal-level timing calibration. In this paper, both simulation and experimental studies were performed to demonstrate the effectiveness and robustness of the TV merge method. We compare the timing resolutions of a 22Na point source, which was located in the field of view (FOV) of the brain PET system, with various calibration techniques. After implementing the TV merge method, the timing resolution improved from 3.34 ns at full width at half maximum (FWHM) to 2.31 ns FWHM. |
| Databáze: | OpenAIRE |
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