Clinical Outcomes of Cerebral Infarctions in Neonates

Autor: So Ick Jang, Sung Koo Kim, Il Tae Hwang, Yoon Young Yi, Jun Sook Lee, Seung Yang, Joon Sup Song, Kyoung Ja Lim
Rok vydání: 2011
Předmět:
Zdroj: Pediatric Neurology. 45:368-372
ISSN: 0887-8994
Popis: Cerebral infarctions are uncommon in neonates. However, they should be considered among causes of neonatal seizures. We describe seven neonates with cerebral infarctions. Clinical presentations, perinatal history, perinatal risk factors, cranial magnetic resonance imaging and electroencephalography findings, thrombophilic factors, and clinical outcomes were reviewed. Six patients manifested seizures, whereas one exhibited cyanosis. Six neonates manifested left middle cerebral artery infarctions, and one exhibited a borderzone infarction between the anterior cerebral and middle cerebral arteries. Electroencephalograms indicated epileptiform discharges on the left hemisphere in three neonates with left middle cerebral artery territory infarctions, and epileptiform discharges on both hemispheres in one patient. At most recent follow-up visit, five patients had achieved normal development, whereas one exhibited right hemiparesis and aphasia, and another manifested toe-in gait. These findings may help predict neurodevelopmental outcomes in neonates with cerebral infarctions.
Databáze: OpenAIRE