Effect of training and detraining on skeletal muscle glucose transporter (GLUT4) content in rats

Autor: Shinebarger Mh, Dohm Gl, Neufer Pd
Rok vydání: 1992
Předmět:
Zdroj: Canadian Journal of Physiology and Pharmacology. 70:1286-1290
ISSN: 1205-7541
0008-4212
Popis: The aim of the present study was to examine the effects of treadmill exercise training and detraining on the skeletal muscle fiber type specific expression of the insulin-regulated glucose transporter protein (GLUT4) in rats. GLUT4 protein content was determined by Western and dot-blot analysis, using a polyclonal antibody raised against the carboxy-terminal peptide. Rats were sacrificed 24 h after the last training session. There were no significant changes in muscle GLUT4 after 1 day or 1 week of training. Six weeks of training increased GLUT4 protein content 1.4- to 1.7-fold (p
Databáze: OpenAIRE