Isavuconazole Treatment of Invasive Fungal Sinusitis: A Post Hoc Analysis of the SECURE and VITAL Trials
| Autor: | Francisco M. Marty, Yi Song, Marlene L. Durand, Therese M Kitt |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Microbiology (medical) medicine.medical_specialty Antifungal Agents Pyridines 030106 microbiology 03 medical and health sciences 0302 clinical medicine Diabetes mellitus Internal medicine Post-hoc analysis Nitriles medicine Overall survival Aspergillosis Humans Mucormycosis Sinusitis 030223 otorhinolaryngology Invasive fungal sinusitis business.industry Triazoles medicine.disease Fungal sinusitis Infectious Diseases business Invasive Fungal Infections |
| Zdroj: | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 73(6) |
| ISSN: | 1537-6591 |
| Popis: | This post hoc analysis of international phase III isavuconazole trials identified 50 patients (90% immunocompromised or diabetic) with invasive fungal sinusitis (88% mucormycetes, Aspergillus) who received isavuconazole as primary (n = 33) or salvage (n = 17) therapy for a median of 82 days (range, 2–882). Overall survival was 82% at day 42 and 70% at day 84. |
| Databáze: | OpenAIRE |
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