Clinicopathological insights into lupus nephritis in South Africans: a study of 251 patients
| Autor: | Brian Rayner, Maureen Duffield, Nicki Tiffin, Charles R. Swanepoel, Ikechi G. Okpechi |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Urinalysis Biopsy Lupus nephritis MEDLINE Rheumatology medicine Humans Aged Cell Proliferation Retrospective Studies Sex Characteristics medicine.diagnostic_test business.industry Retrospective cohort study Middle Aged medicine.disease Lupus Nephritis Dermatology Female Renal biopsy business Sex characteristics |
| Zdroj: | Lupus. 21:1017-1024 |
| ISSN: | 1477-0962 0961-2033 |
| DOI: | 10.1177/0961203312441981 |
| Popis: | There are few published studies on biopsy proven lupus nephritis (LN) from sub-Sahara Africa, mainly due to lack of expertise and pathology back-up for performing and interpreting renal biopsies in many centres. The purpose of this study was to document factors associated with biopsy proven LN and to determine clinical and laboratory models that best predict proliferative LN in South Africans. Of the 251 patients studied, 84.1% were females and 79.3% were of mixed ancestry. There were more observed cases of proliferative LN (63%) than non-proliferative LN. Factors associated with proliferative LN were male gender ( p = 0.049), haematuria on dipstix ( p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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