Cardiac surgery antibiotic prophylaxis and calculated empiric antibiotic therapy
| Autor: | Christoph Schimmer, Khaled Hamouda, Armin Gorski, Rainer Leyh, Sebastian-Patrick Sommer, Markus Leistner, M. Özkur |
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| Rok vydání: | 2014 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty business.industry Bacterial Infections General Medicine Antibiotic Prophylaxis Drug Administration Schedule Anti-Bacterial Agents Cardiac surgery Treatment Outcome Surveys and Questionnaires Antibiotic therapy medicine Humans Surgical Wound Infection Surgery Cardiac Surgical Procedures Antibiotic prophylaxis Cardiology and Cardiovascular Medicine Intensive care medicine business |
| Zdroj: | Asian Cardiovascular and Thoracic Annals. 23:282-288 |
| ISSN: | 1816-5370 0218-4923 |
| Popis: | BackgroundOngoing debate exists concerning the optimal choice and duration of antibiotic prophylaxis as well as the reasonable calculated empiric antibiotic therapy for hospital-acquired infections in critically ill cardiac surgery patients.MethodsA nationwide questionnaire was distributed to all German heart surgery centers concerning antibiotic prophylaxis and the calculated empiric antibiotic therapy.ResultsThe response to the questionnaire was 87.3%. All clinics that responded use antibiotic prophylaxis, 79% perform it not longer than 24 h (single-shot: 23%; 2 doses: 29%; 3 doses: 27%; 4 doses: 13%; and >5 doses: 8%). Cephalosporin was used in 89% of clinics (46% second-generation, 43% first-generation cephalosporin). If sepsis is suspected, the following diagnostics are performed routinely: wound inspection 100%; white blood cell count 100%; radiography 99%; C-reactive protein 97%; microbiological testing of urine 91%, blood 81%, and bronchial secretion 81%; procalcitonin 74%; and echocardiography 75%. The calculated empiric antibiotic therapy (depending on the suspected focus) consists of a multidrug combination with broad-spectrum agents.ConclusionThis survey shows that existing national guidelines and recommendations concerning perioperative antibiotic prophylaxis and calculated empiric antibiotic therapy are well applied in almost all German heart centers. |
| Databáze: | OpenAIRE |
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