A clinical decision support system to improve adequate dosing of gentamicin and vancomycin
| Autor: | Ruud T.M. van der Hoeven, Sjoerd L. Verweij, Marieke Pereboom, Inge J. Mulder, Matthijs L. Becker |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Drug
Adult Male medicine.medical_specialty 020205 medical informatics Adolescent media_common.quotation_subject Health Informatics 02 engineering and technology Clinical decision support system 03 medical and health sciences Young Adult 0302 clinical medicine Vancomycin 0202 electrical engineering electronic engineering information engineering medicine Humans 030212 general & internal medicine Dosing Child media_common Aged Netherlands Aged 80 and over business.industry Infant Newborn Infant Middle Aged Decision Support Systems Clinical Intervention studies Anti-Bacterial Agents Child Preschool Emergency medicine Plasma concentration Patient Compliance Gentamicin Female Drug Monitoring Gentamicins business medicine.drug |
| Zdroj: | International journal of medical informatics. 124 |
| ISSN: | 1872-8243 |
| Popis: | Gentamicin and vancomycin meet the criteria for measuring plasma concentrations during therapy. However, compliance with the accompanying guidelines remains low. The primary objective of this study was to determine whether the implementation of a clinical decision support system, which displays an alert if a plasma concentration should be measured and a daily reviewed patient list resulted in improved compliance.This intervention study was performed at the Spaarne Gasthuis, Haarlem/Hoofddorp, the Netherlands. The authors included 261 treatments with either gentamicin or vancomycin intravenously for at least 48 h in the year before and after implementation of the clinical decision support system in May 2015. The authors analyzed whether plasma concentrations were measured sooner and more frequently after the implementation, and determined whether the time until the correct dosage, with adequate drug concentrations, was reduced after implementation.Before implementation, plasma concentrations were measured within 72 h in 47% of the treatments. After implementation, this percentage increased to 80% (p 0.01). After implementation, the time was significantly shorter until the correct dosage was given.The implementation of a clinical decision support system and a patient list resulted in improved compliance with the guidelines and optimized the treatment with gentamicin and vancomycin. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect