The relationship of serum and salivary cortisol levels to male sexual dysfunction as measured by the International Index of Erectile Function
| Autor: | Yoshitomo Kobori, Kazutaka Narimoto, Teruaki Iwamoto, Mikio Namiki, Tomohiko Matsushita, Yuji Maeda, Eitetsu Koh, Koji Izumi, Hiroyuki Konaka, Kazuhiro Sugimoto, Atsushi Mizokami |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Saliva Aging Hydrocortisone erectile dysfunction Urology cortisol Mass Spectrometry Tandem Mass Spectrometry Internal medicine Surveys and Questionnaires medicine Humans Testosterone Chromatography High Pressure Liquid Aged business.industry Depression Penile Erection Original Articles Middle Aged medicine.disease Antidepressive Agents Endocrinology Sexual dysfunction Erectile dysfunction testosterone Population study medicine.symptom business Sexual function liquid chromatography/tandem mass spectrometry medicine.drug Hormone Penis |
| Zdroj: | International Journal of Impotence Research |
| ISSN: | 1476-5489 |
| Popis: | To evaluate the biomarkers of sexual function, we investigated the relationship between questionnaire responses and biological hormones such as testosterone (T) and cortisol (F) in serum and saliva. The study population included 105 men aged 30–72 years (mean: 49±4.5, median: 49). Levels of all serum hormones (Total-T, Free-T, Bioavailable-T, Total-F and Bioavailable-F) and salivary hormones (Saliva-T and Saliva-F) were measured directly by liquid chromatography/tandem mass spectrometry. The International Index of Erectile Function (IIEF) was used as a questionnaire to evaluate sexual dysfunction. Free-T and Bioavailable-T showed significant inverse correlations with age (P |
| Databáze: | OpenAIRE |
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