Physical Activity and Cardiorespiratory Fitness Are Beneficial for White Matter in Low-Fit Older Adults

Autor: Erin A. Olson, Elisabeth Awick, Jason Fanning, Andrew Lewis, Edward McAuley, Michelle W. Voss, Jim M. Monti, Anya M. Knecht, Agnieszka Z. Burzynska, Laura Chaddock-Heyman, Gillian E. Cooke, Chelsea N. Wong, Thomas R. Wójcicki, Hyondo D. Chung, Arthur F. Kramer, Neha P. Gothe
Rok vydání: 2014
Předmět:
Male
Gerontology
Aging
Physiology
Physical fitness
lcsh:Medicine
Diagnostic Radiology
Cognition
0302 clinical medicine
Medicine and Health Sciences
lcsh:Science
Brain Mapping
0303 health sciences
Multidisciplinary
Age Factors
Sedentary behavior
Middle Aged
Magnetic Resonance Imaging
White Matter
Diffusion Tensor Imaging
medicine.anatomical_structure
Female
Research Article
medicine.medical_specialty
Brain Morphometry
Physical activity
Neuroimaging
Motor Activity
White matter
03 medical and health sciences
Sex Factors
Physical medicine and rehabilitation
Diagnostic Medicine
Echo Planar Imaging
medicine
Humans
Sports and Exercise Medicine
Exercise
Life Style
Aged
030304 developmental biology
Sedentary lifestyle
Neural correlates of consciousness
business.industry
lcsh:R
Biology and Life Sciences
Cardiorespiratory fitness
Physical Fitness
lcsh:Q
Sedentary Behavior
Physiological Processes
business
Organism Development
030217 neurology & neurosurgery
Developmental Biology
Neuroscience
Zdroj: PLoS ONE
PLoS ONE, Vol 9, Iss 9, p e107413 (2014)
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0107413
Popis: Physical activity (PA) and cardiorespiratory fitness (CRF) are associated with better cognitive function in late life, but the neural correlates for these relationships are unclear. To study these correlates, we examined the association of both PA and CRF with measures of white matter (WM) integrity in 88 healthy low-fit adults (age 60-78). Using accelerometry, we objectively measured sedentary behavior, light PA, and moderate to vigorous PA (MV-PA) over a week. We showed that greater MV-PA was related to lower volume of WM lesions. The association between PA and WM microstructural integrity (measured with diffusion tensor imaging) was region-specific: light PA was related to temporal WM, while sedentary behavior was associated with lower integrity in the parahippocampal WM. Our findings highlight that engaging in PA of various intensity in parallel with avoiding sedentariness are important in maintaining WM health in older age, supporting public health recommendations that emphasize the importance of active lifestyle.
Databáze: OpenAIRE
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