A comparison of two optical coherence tomography–angiography devices in pseudoexfoliation glaucoma versus primary open-angle glaucoma and healthy subjects
| Autor: | Sara Ortiz-Toquero, Gema Rebolleda, Ane Pérez-Sarriegui, Victoria de Juan, Francisco J. Muñoz-Negrete |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Retinal Ganglion Cells medicine.medical_specialty genetic structures Open angle glaucoma Optic Disk Glaucoma Exfoliation Syndrome 03 medical and health sciences Nerve Fibers 0302 clinical medicine Pseudoexfoliation glaucoma Ophthalmology Humans Medicine Fluorescein Angiography Intraocular Pressure Aged Aged 80 and over business.industry Healthy subjects Retinal Vessels General Medicine Optical coherence tomography angiography Middle Aged medicine.disease Healthy Volunteers eye diseases Cross-Sectional Studies 030221 ophthalmology & optometry Visual Field Tests Female sense organs Visual Fields business Glaucoma Open-Angle Tomography Optical Coherence 030217 neurology & neurosurgery |
| Zdroj: | European Journal of Ophthalmology. 29:636-644 |
| ISSN: | 1724-6016 1120-6721 |
| Popis: | Purpose:To compare peripapillary vascular parameters derived from two optical coherence tomography angiography devices in pseudoexfoliation glaucoma, primary open-angle glaucoma, and healthy controls and to evaluate their diagnostic accuracy.Methods:Observational, cross-sectional study. In total, 20 eyes with pseudoexfoliation glaucoma, 20 primary open-angle glaucoma eyes matched by peripapillary retinal nerve fiber layer thickness, and 20 control eyes were recruited. Participants underwent standard automated perimetry and peripapillary retinal nerve fiber layer analysis by Optovue and Cirrus optical coherence tomography. Vascular parameters provided by Angiovue and Angioplex optical coherence tomography angiography were compared. Their diagnostic accuracy and correlation with structural and functional parameters were assessed.Results:All peripapillary optical coherence tomography angiography vascular parameters were significantly different among groups (all p Conclusion:Only Angiovue detected a significantly lower capillary density in pseudoexfoliation glaucoma compared to primary open-angle glaucoma at similar glaucoma damage. Both, Angiovue and Angioplex demonstrated a decreased capillary density in glaucoma eyes compared to healthy eyes. Furthermore, Angiovue-derived vascular parameters showed better correlation with functional and structural parameters and a higher diagnostic capacity to discriminate among groups compared to Angioplex. |
| Databáze: | OpenAIRE |
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