Utility of point-of-care malaria rapid diagnostic tests
| Autor: | Van den Ende J, Bisoffi Z, Jan Jacobs |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Adult
Male Rural Population medicine.medical_specialty Fever Point-of-Care Systems malaaria Plasmodium falciparum Predictive value HIV Infections rapid diagnostic test Sensitivity and Specificity Mosquitoes Sensitivity Predictive Value of Tests Virology medicine Humans Uganda Intensive care medicine Letter to the Editor Accuracy Point of care Rapid diagnostic test business.industry Rapid diagnostic tests Diagnostic test malaaria rapid diagnostic test Middle Aged Protozoal diseases Vectors medicine.disease Malaria Infectious Diseases Immunology Parasitology Female business |
| Zdroj: | The American Journal of Tropical Medicine and Hygiene |
| Popis: | We compared results of a malaria rapid diagnostic test (Binax Now Malaria, Binax-M, Inverness Medical Innovations, Inc., Waltham, MA) performed at rural mobile clinics in Uganda by clinicians evaluating febrile adult HIV patients to thick smear evaluated at a central laboratory by trained microscopists. Two hundred forty-six samples were analyzed, including 14 (5.7%) which were thick-smear positive for falciparum malaria. Sensitivity of Binax-M compared with thick smear was 85.7% (95% CI: 57.2-98.2), specificity 97.8% (95% CI: 94.9-99.3), positive and negative predictive values were 70.6% (95% CI: 44.0-89.7) and 99.1% (95% CI: 96.8-99.9), respectively. The rapid diagnostic test accurately ruled malaria "in or out" at the point-of-care, facilitating appropriate clinical management and averting unnecessary anti-malarial therapy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|