Neonatal haemoglobinopathy screening in Burkina Faso
| Autor: | Mamadou Sawadogo, J Ayéroué, Eleonore Kafando, Frédéric Cotton, Youssouf Ouattara, Béatrice Gulbis, Eric William Camille Nacoulma |
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| Rok vydání: | 2008 |
| Předmět: |
medicine.medical_specialty
Pediatrics business.industry Medical screening Incidence (epidemiology) Infant Newborn Cord blood sampling General Medicine medicine.disease Pathology and Forensic Medicine Dried blood spot Hemoglobinopathies Screening programme Neonatal Screening Hemoglobinopathy Recien nacido Burkina Faso Outcome Assessment Health Care Epidemiology medicine Feasibility Studies Humans Isoelectric Focusing business Developing Countries |
| Zdroj: | Journal of Clinical Pathology. 62:39-41 |
| ISSN: | 0021-9746 |
| Popis: | Aims: To report our experience of neonatal screening for sickle cell disease in Ouagadougou (Burkina Faso) and to discuss the feasibility of neonatal screening in this country. Methods: Between the years 2000 and 2004, there were about 2341 births in five maternity services in Ouagadougou. These babies were screened for sickle cell disease in a universal screening pilot programme. In 2006, 53 babies born to selected couples were screened. The specimens were collected either by cord blood sampling or from a dried blood spot on filter paper. The screening was performed using an isoelectric focusing technique. Results: In the first stage (2000–4), the incidence of sickle cell disease was 1:57. In the second stage, six of 53 babies of selected couples were found to have major haemoglobinopathies: one was homozygous for haemoglobin S and five were compound heterozygotes for haemoglobins S and C. Conclusions: The results suggest that a national screening programme should be implemented in Burkina Faso with effective newborn and subsequent follow-up, but a methodology needs to be developed. |
| Databáze: | OpenAIRE |
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