The ultrastructure of oesophageal carcinomas: multidirectional differentiation. A transmission electron microscopic study of 43 cases
| Autor: | H.R. Matthews, J Newman, G N Antonakopoulos, S J Darnton |
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| Rok vydání: | 1992 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Esophageal Neoplasms Adenosquamous carcinoma Cell Biology Adenocarcinoma Cytoplasmic Granules Microtubules Pathology and Forensic Medicine law.invention law medicine Carcinoma Humans Tumor type Esophagus Carcinoma Small Cell Electron microscopic Aged Aged 80 and over Cell Polarity Desmosomes Middle Aged medicine.disease stomatognathic diseases Microscopy Electron medicine.anatomical_structure Cell Transformation Neoplastic Ultrastructure Carcinoma Squamous Cell Female Electron microscope |
| Zdroj: | The Journal of pathology. 167(2) |
| ISSN: | 0022-3417 |
| Popis: | Forty-three oesophageal carcinomas, comprising 15 squamous cell carcinomas, 22 adenocarcinomas, 5 small cell carcinomas, and 1 adenosquamous carcinoma, were examined by transmission electron microscopy. The ultrastructural features of each tumour type are detailed. Multi-directional differentiation (heterogeneity) was observed in 11 cases: 5 squamous cell carcinomas with focal glandular features; 4 adenocarcinomas with focal squamous features; and 2 small cell carcinomas, one with glandular and the other with squamous features. Abnormal distributions of desmosomes in squamous cell carcinomas and of polarity of tumour cells in adenocarcinomas are described. |
| Databáze: | OpenAIRE |
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