Clinical Usefulness of ELISPOT Assay on Pericardial Fluid in a Case of Suspected Tuberculous Pericarditis
| Autor: | G. Montrucchio, Alberto Biglino, C. Bolla, P. Crivelli, E Concialdi |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty business.industry Tuberculous pericarditis ELISPOT medicine.medical_treatment Pericardial fluid Enzyme-Linked Immunosorbent Assay Mycobacterium tuberculosis Pericarditis Tuberculous General Medicine Middle Aged medicine.disease Pericardial Effusion Cardiac Tamponade Surgery Interferon-gamma Infectious Diseases Pericardiocentesis medicine Humans Female Tamponade business |
| Zdroj: | Infection. 36:601-604 |
| ISSN: | 1439-0973 0300-8126 |
| DOI: | 10.1007/s15010-008-7402-y |
| Popis: | Rapid and accurate diagnosis of tuberculous pericarditis is often difficult, considering the low specificity of both clinical picture and laboratory tests on pericardial fluid, as well as the low sensitivity of microbiological tests. This report documents the feasibility and clinical usefulness of an Interferon (IFN) - gamma ELISpot - TB assay on pericardial fluid cells in a case of suspected tuberculous pericarditis presenting with tamponade. As large pericardial effusions requiring pericardiocentesis are relatively frequent in tuberculous pericarditis, the physician may consider this particular application of ELISpot-TB as a rapid decision aid for starting the treatment. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink