Behavioral profile assessment in offspring of Swiss mice treated during pregnancy and lactation with caffeine
| Autor: | Anderson Luiz Bezerra da Silveira, Claudio Silva-Almeida, Fábio Fagundes da Rocha, Fernando A.C. Seara, Wellington da Silva Côrtes, Bruno Guimarães Marinho, Roberto Laureano-Melo, Luís Carlos Reis, Rodrigo Rodrigues da Conceição |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Male Elevated plus maze Offspring Physiology Anxiety Motor Activity Biochemistry Open field Marble burying 03 medical and health sciences Cellular and Molecular Neuroscience chemistry.chemical_compound Mice 0302 clinical medicine Pregnancy Lactation Caffeine medicine Nociception assay Animals Maze Learning medicine.disease 030104 developmental biology medicine.anatomical_structure chemistry Hyperalgesia Anesthesia Prenatal Exposure Delayed Effects Central Nervous System Stimulants Female Neurology (clinical) Psychology 030217 neurology & neurosurgery |
| Zdroj: | Metabolic brain disease. 31(5) |
| ISSN: | 1573-7365 |
| Popis: | The association between caffeine consumption and various psychiatric manifestations has long been observed. The objective was to assess the behavioral profile in offspring of Swiss mice treated during pregnancy and lactation with caffeine. For this purpose, two groups (n = 6 each and BW ~ 35 g) of female mice were treated during pregnancy and lactation by: tap water and caffeine solution at a concentration of 0.3 mg/mL through oral route. The offspring obtained, by completing 70 days of life, was underwent a behavioral battery test. Statistical analysis was performed by student t test and the different significance adopted was p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink