Prevalence of depression in patients with type 2 diabetes mellitus in Spain (the DIADEMA Study) : results from the MADIABETES cohort
| Autor: | Miguel Angel, Salinero-Fort, P, Gómez-Campelo, F Javier, San Andrés-Rebollo, Juan, Cárdenas-Valladolid, Juan C, Abánades-Herranz, Enrique, Carrillo de Santa Pau, Rosa M, Chico-Moraleja, Domingo, Beamud-Victoria, Jose M, de Miguel-Yanes, Rodrigo, Jimenez-Garcia, Ana, López-de-Andres, Yolanda, Ramallo-Fariña, Carmen, De Burgos-Lunar, M P, Zazo-Lázaro |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty endocrine system diseases Health Status Population 030209 endocrinology & metabolism 03 medical and health sciences 0302 clinical medicine Sex Factors cohort studies Risk Factors Internal medicine Diabetes mellitus self-care medicine Prevalence Humans Diabetic Nephropathies 030212 general & internal medicine Prospective Studies education Prospective cohort study Depression (differential diagnoses) Aged Aged 80 and over education.field_of_study business.industry Depression Incidence (epidemiology) Incidence Mental Disorders nutritional and metabolic diseases Type 2 Diabetes Mellitus General Medicine Middle Aged Protective Factors medicine.disease diabetes mellitus type 2 Diabetes Mellitus Type 2 Spain depression Cohort Female business Cohort study |
| Zdroj: | Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid Consejería de Sanidad de la Comunidad de Madrid |
| ISSN: | 2044-6055 |
| Popis: | ObjectiveTo estimate the prevalence of depression in patients diagnosed with type 2 diabetes mellitus (T2DM), and to identify sociodemographic, clinical and psychological factors associated with depression in this population. Additionally, we examine the annual incidence rate of depression among patients with T2DM.MethodsWe performed a large prospective cohort study of patients with T2DM from the Madrid Diabetes Study. The first recruitment drive included 3443 patients. The second recruitment drive included 727 new patients. Data have been collected since 2007 (baseline visit) and annually during the follow-up period (since 2008).ResultsDepression was prevalent in 20.03% of patients (n=592; 95% CI 18.6% to 21.5%) and was associated with previous personal history of depression (OR 6.482; 95% CI 5.138 to 8.178), mental health status below mean (OR 1.423; 95% CI 1.452 to 2.577), neuropathy (OR 1.951; 95% CI 1.423 to 2.674), fair or poor self-reported health status (OR 1.509; 95% CI 1.209 to 1.882), treatment with oral antidiabetic agents plus insulin (OR 1.802; 95% CI 1.364 to 2.380), female gender (OR 1.333; 95% CI 1.009 to 1.761) and blood cholesterol level (OR 1.005; 95% CI 1.002 to 1.009). The variables inversely associated with depression were: being in employment (OR 0.595; 95% CI 0.397 to 0.894), low physical activity (OR 0.552; 95% CI 0.408 to 0.746), systolic blood pressure (OR 0.982; 95% CI 0.971 to 0.992) and social support (OR 0.978; 95% CI 0.963 to 0.993). In patients without depression at baseline, the incidence of depression after 1 year of follow-up was 1.20% (95% CI 1.11% to 2.81%).ConclusionsDepression is very prevalent among patients with T2DM and is associated with several key diabetes-related outcomes. Our results suggest that previous mental status, self-reported health status, gender and several diabetes-related complications are associated with differences in the degree of depression. These findings should alert practitioners to the importance of detecting depression in patients with T2DM. |
| Databáze: | OpenAIRE |
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