Estimation of Ventricular Repolarization in Man by Monophasic Action Potential Recording Technique
| Autor: | S. B. Olsson, N. Edvardsson, E. Varnauskas, L. Brorson |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Cardiac Catheterization
medicine.medical_specialty Ventricular Repolarization Atrial action potential Heart Ventricles Signal Electrocardiography Heart Conduction System Internal medicine medicine Humans Heart Atria cardiovascular diseases Atrium (heart) Electrodes business.industry Time constant Cardiac arrhythmia Electrophysiology Heart Block medicine.anatomical_structure cardiovascular system Cardiology Cardiology and Cardiovascular Medicine business Endocardium Anti-Arrhythmia Agents |
| Zdroj: | European Heart Journal. 6:71-79 |
| ISSN: | 1522-9645 0195-668X |
| Popis: | Myocardial monophasic action potentials (MAP) can be recorded with the aid of suction or contact electrodes applied endocardially via a catheter. The technique necessitates high input impedance amplifiers with infinite time constant. A bipolar technique improves signal quality with regard to electrical contamination around the rapid upstroke of the MAP. Mechanical artefacts in the recordings are common and may be explained by catheter movement induced by atrial or ventricular contractions. The MAP signal can be used for a precise measurement of time of local excitation and for the study of atrial as well as ventricular repolarization. The technique has mostly been applied in the exploration of atrial and ventricular repolarization in healthy hearts and during different cardiac arrhythmias. Furthermore, several studies have documented the electrophysiological action of antiarrhythmic drugs upon the human heart. Concluding from 576 different investigations we consider the technique to have no serious side-effects. |
| Databáze: | OpenAIRE |
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