Decade-long trends in the characteristics, management and hospital outcomes of diabetic patients with ST-segment elevation myocardial infarction

Autor: Samuel W. Joffe, Robert J. Goldberg, Jorge L. Yarzebski, Darleen M. Lessard, Chad E. Darling, David D. McManus, Joel M. Gore, Mayra Tisminetzky
Rok vydání: 2014
Předmět:
Male
medicine.medical_specialty
Endocrinology
Diabetes and Metabolism

medicine.medical_treatment
Adrenergic beta-Antagonists
Myocardial Infarction
Angiotensin-Converting Enzyme Inhibitors
Article
Body Mass Index
Cohort Studies
Diabetes Complications
Angiotensin Receptor Antagonists
Percutaneous Coronary Intervention
Diabetes mellitus
Internal medicine
Diabetes Mellitus
Internal Medicine
medicine
Humans
Hospital Mortality
Myocardial infarction
Coronary Artery Bypass
Aged
Retrospective Studies
Aspirin
business.industry
Medical record
Age Factors
Case-control study
Percutaneous coronary intervention
Retrospective cohort study
Length of Stay
Middle Aged
Prognosis
medicine.disease
Treatment Outcome
Case-Control Studies
Cardiology
Platelet aggregation inhibitor
Female
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Cardiology and Cardiovascular Medicine
business
Platelet Aggregation Inhibitors
Cohort study
Zdroj: Diabetes and Vascular Disease Research. 11:182-189
ISSN: 1752-8984
1479-1641
DOI: 10.1177/1479164114524235
Popis: Purpose: Our objectives were to describe recent trends in the characteristics and in-hospital outcomes in diabetic as compared with non-diabetic patients hospitalized with ST-segment elevation myocardial infarction (STEMI). Methods: We reviewed the medical records of 2537 persons with (n = 684) and without (n = 1853) a history of diabetes who were hospitalized for STEMI between 1997 and 2009 at 11 medical centres in Central Massachusetts. Results: Diabetic patients were more likely to be older, female and to have a higher prevalence of previously diagnosed comorbidities. Diabetic patients were more likely to have developed important in-hospital complications and to have a longer hospital stay compared with non-diabetic patients. Between 1997 and 2009, there was a marked decline in hospital mortality in diabetic (20.0%–5.6%) and non-diabetic (18.6%–7.5%) patients. Conclusion: Despite reduced hospital mortality in patients hospitalized with STEMI, diabetic patients continue to experience significantly more adverse outcomes than non-diabetics.
Databáze: OpenAIRE