Applying an intraoperative predictive indicator for postoperative pancreatic fistula: randomized preclinical trial
| Autor: | F K F Kommoss, C Mitzscherling, O Aubert, Thomas Pausch, Thomas Bruckner, B Gesslein, M Golriz, Arianeb Mehrabi, Xinchun Liu, Thilo Hackert |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Intra operative 030230 surgery Pancreatic Fistula Random Allocation 03 medical and health sciences Pancreatectomy Postoperative Complications 0302 clinical medicine Text mining Polysaccharides Animals Medicine Coloring Agents Intraoperative Complications Laparotomy business.industry food and beverages medicine.disease Microspheres Surgery Disease Models Animal Pancreatic fistula 030220 oncology & carcinogenesis Amylases Pancreatic juice Bromthymol Blue Drainage business |
| Zdroj: | British Journal of Surgery. 108:235-238 |
| ISSN: | 1365-2168 0007-1323 |
| Popis: | Leaking pancreatic fluid can contribute to postoperative pancreatic fistula (POPF), which can complicate pancreatic surgery. Surgeons lack reliable tools to identify pancreatic leaks, so a novel hydrogel indicator called SmartPAN was developed for intraoperative application. In this preclinical efficacy assessment study, SmartPAN was capable of detecting sites associated with biochemical leak and POPF-related symptoms, thereby guiding effective closure. Thus, SmartPAN may help to reduce POPF development in upcoming clinical trials. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|