Effects of a modestly lower carbohydrate diet in gestational diabetes: a randomized controlled trial
| Autor: | Glynis P. Ross, Fiona S. Atkinson, Jovana Mijatovic, Jimmy Chun Yu Louie, Marion E. C. Buso, Tania P. Markovic, Jennie Brand-Miller |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Blood Glucose ketones Birth weight Medicine (miscellaneous) Physiology 030209 endocrinology & metabolism Body Mass Index law.invention Test strips Diet Carbohydrate-Restricted 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Pregnancy lower carbohydrate law Dietary Carbohydrates Humans MAMI study Medicine Clinical significance 030212 general & internal medicine Finger prick Global Nutrition Wereldvoeding Nutrition and Dietetics business.industry Carbohydrate medicine.disease Gestational diabetes Diabetes Gestational Glycemic Index Female gestational diabetes Energy Intake diet business metabolism |
| Zdroj: | The American journal of clinical nutrition 112 (2020) 2 The American journal of clinical nutrition, 112(2), 284-292 |
| ISSN: | 0002-9165 |
| Popis: | BACKGROUND: Lower carbohydrate diets have the potential to improve glycemia but may increase ketonemia in women with gestational diabetes (GDM). We hypothesized that modestly lower carbohydrate intake would not increase ketonemia. OBJECTIVE: To compare blood ketone concentration, risk of ketonemia, and pregnancy outcomes in women with GDM randomly assigned to a lower carbohydrate diet or routine care. METHODS: Forty-six women aged (mean ± SEM) 33.3 ± 0.6 y and prepregnancy BMI 26.8 ± 0.9 kg/m2 were randomly assigned at 28.5 ± 0.4 wk to a modestly lower carbohydrate diet (MLC, ∼135 g/d carbohydrate) or routine care (RC, ∼200 g/d) for 6 wk. Blood ketones were ascertained by finger prick test strips and 3-d food diaries were collected at baseline and end of the intervention. RESULTS: There were no detectable differences in blood ketones between completers in the MLC group compared with the RC group (0.1 ± 0.0 compared with 0.1 ± 0.0 mmol/L, n = 33, P = 0.31, respectively), even though carbohydrate and total energy intake were significantly lower in the intervention group (carbohydrate 165 ± 7 compared with 190 ± 9 g, P = 0.04; energy 7040 ± 240 compared with 8230 ± 320 kJ, P |
| Databáze: | OpenAIRE |
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