Isolation of Toxoplasma gondii strains similar to Africa 1 genotype in Turkey
| Autor: | Metin Korkmaz, Kürşat Altintaş, Derya Dirim Erdogan, Ahmet Üner, Hüseyin Can, Yüksel Gürüz, Aysu Değirmenci, Daniel Ajzenberg, Ayşe Caner, Mert Döşkaya, Çiğdem Güngör, Marie-Laure Dardé |
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| Přispěvatelé: | Neuroépidémiologie Tropicale (NET), Institut Génomique, Environnement, Immunité, Santé, Thérapeutique (GEIST), Université de Limoges (UNILIM)-Université de Limoges (UNILIM)-CHU Limoges-Institut d'Epidémiologie Neurologique et de Neurologie Tropicale-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de Référence (CNR) Toxoplasmose/Toxoplasma Biological Resource Center (BRC) (CNR Toxoplasmose-Toxoplasma BRC), CHU Limoges, Université de Limoges (UNILIM) |
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Genotype
Turkey 030231 tropical medicine Antibodies Protozoan Toxoplasmosis Congenital 03 medical and health sciences 0302 clinical medicine parasitic diseases medicine Parasite hosting Animals Humans 030304 developmental biology 0303 health sciences biology Infant Newborn Toxoplasma gondii medicine.disease biology.organism_classification Isolation (microbiology) Virology Congenital toxoplasmosis 3. Good health Infectious Diseases Microsatellite Analysis Treatment strategy Parasitology [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie Toxoplasma Encephalitis Microsatellite Repeats |
| Zdroj: | Parasitology International Parasitology International, Elsevier, 2013, 62 (5), pp.471-4. ⟨10.1016/j.parint.2013.06.008⟩ |
| ISSN: | 1383-5769 |
| Popis: | International audience; INTRODUCTION: Toxoplasma gondii is a protozoon parasite that has a worldwide dissemination. It can cause serious clinical problems such as congenital toxoplasmosis, retinochoroiditis, and encephalitis. Currently, T. gondii genotypes are being associated with these clinical presentations which may help clinicians design their treatment strategy. CASE REPORTS: Two T. gondii strains named Ankara and Ege-1 were isolated from newborns with congenital toxoplasmosis in Central and Western Anatolia, respectively. Ankara and Ege-1 strains were isolated from the cerebrospinal fluid of newborns. According to microsatellite analysis, Ankara and Ege-1 strains were sorted as Africa 1 genotype. CONCLUSION: T. gondii strains isolated in Turkey were first time genotyped in this study. Africa 1 genotype has previously been isolated in immunosuppressed patients originating from sub-Saharan Africa. The reason of detecting a strain mainly detected in Africa can be associated with Turkey's specific geographical location. Turkey is like a bridge between Asia, Europe and Africa. Historically, Anatolia was on the Silk Road and other trading routes that ended in Europe. Thus, detecting Africa 1 strain in Anatolia can be anticipated. Consequently, strains detected mainly in Europe and Asia may also be detected in Anatolia and vice versa. Therefore, further studies are required to isolate more strains from Turkey. |
| Databáze: | OpenAIRE |
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