Pachymetric mapping with Fourier-domain optical coherence tomography
Autor: | Jose Luiz Branco Ramos, David Huang, Xinbo Zhang, Yan Li, Maolong Tang, Camila Salaroli |
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Rok vydání: | 2010 |
Předmět: |
Adult
Male medicine.medical_specialty genetic structures Microscopy Acoustic Visual Acuity Article Pupil Cornea Young Adult Optical coherence tomography Reference Values Ophthalmology medicine Humans Fourier domain Anthropometry Fourier Analysis medicine.diagnostic_test business.industry Ultrasound Corneal Topography Reproducibility of Results Repeatability Middle Aged Corneal topography eye diseases Sensory Systems medicine.anatomical_structure Optometry Female Surgery sense organs Tomography business Tomography Optical Coherence |
Zdroj: | Journal of Cataract and Refractive Surgery. 36:826-831 |
ISSN: | 0886-3350 |
DOI: | 10.1016/j.jcrs.2009.11.016 |
Popis: | To evaluate the repeatability of Fourier-domain optical coherence tomography (OCT) pachymetric mapping and compare central corneal thickness (CCT) measurements by OCT, ultrasound pachymetry, and scanning-slit tomography.Doheny Eye Institute, University of Southern California, Los Angeles, California, USA.A Fourier-domain OCT system was used to map the corneal thickness in normal eyes with scans centered on the corneal vertex or the pupil. Repeatability of central and pericentral map sectors was assessed by pooled standard deviation. The CCT measurements were compared between the OCT, ultrasound, and scanning-slit devices.Pupil centration (SD: 1.3 microm central, 1.8 to 3.8 microm pericentral) provided better repeatability than vertex centration (SD: 1.7 microm central, 2.4 to 5.7 microm pericentral) in all sectors (P.035). The mean CCT was 536.9 microm +/- 27.0 (SD) by OCT, 556.6 +/- 30.5 microm by ultrasound, and 537.2 +/- 32.6 microm by scanning-slit tomography (acoustic factor 0.92). The CCT measured by OCT was significantly thinner than by ultrasound pachymetry (P = .007; mean difference -19.7 microm; 95% limits of agreement [LoA], -40.4 to 0.9 microm) but not than by scanning-slit tomography (P = .2637; mean difference -0.3 microm; 95% LoA, -24.0 to 23.5 microm). The CCT by OCT correlated well with ultrasound and scanning-slit CCTs (r = 0.940 and r = 0.934, respectively).Pachymetric mapping with Fourier-domain OCT was highly repeatable. Repeatability was better with pupil-centered scans than with corneal vertex-centered scans. Ultrasound pachymetry, Fourier-domain OCT, and scanning-slit tomography should not be used interchangeably for CCT assessment. |
Databáze: | OpenAIRE |
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