In vitro effects of protein fractions from Controne beans (Phaseolus vulgaris L. ecotype Controne) on intestinal permeability, ACE and α-amylase activities
Autor: | Connie Schisano, Viviana Narciso, Giuseppe Annunziata, Ettore Novellino, Gian Carlo Tenore, Maria Maisto, Paolo Grieco, Eduardo Sommella |
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Přispěvatelé: | Schisano, Connie, Narciso, Viviana, Maisto, Maria, Annunziata, Giuseppe, Grieco, Paolo, Sommella, Eduardo Maria, Tenore, Gian Carlo, Novellino, Ettore |
Rok vydání: | 2019 |
Předmět: |
Anti-radical activity
Antioxidant 030309 nutrition & dietetics medicine.medical_treatment Intestinal permeability Biochemistry Industrial and Manufacturing Engineering 03 medical and health sciences 0404 agricultural biotechnology Nutraceutical medicine Amylase Food science Alpha-amylase inhibition Legume 0303 health sciences biology Ecotype Chemistry Bean food and beverages Angiotensin-converting enzyme ACE inhibition 04 agricultural and veterinary sciences General Chemistry biology.organism_classification 040401 food science Protein extract biology.protein Mannitol Phaseolus Food Science Biotechnology medicine.drug |
Zdroj: | European Food Research and Technology. 245:2311-2322 |
ISSN: | 1438-2385 1438-2377 |
Popis: | Recent studies suggest that different types of milk-derived proteins or peptides might be active as antihypertensive, antioxidant, immunomodulatory and antimicrobial agents. Nonetheless, the research of an alternative source of bioactive peptides to avoid the different types of allergy and intolerance, caused by milk protein, could be hypothesised. Controne bean (Phaseolus vulgaris L. ecotype Controne) is a typical legume variety from Campania region (Controne Municipality, Salerno, Italy), characterised, on average, by a protein content of 22%. Thus, the aim of this study was to evaluate the in vitro effect of protein extracts (PEs) from different bean cultivars, such as Controne, Spanish White and Cannellini, to verify some peculiar biological properties, such as antiradical, anti α-amylase and angiotensin converting enzyme (ACE) inhibitory activities, as well as to test in vitro the potential influence of PEs on intestinal permeability. The most promising results were provided by Controne cultivar; in particular: antiradical effect, 80%; lactulose/mannitol ratio, LMR, 0.198; α-amylase inhibition, 70%; ACE inhibition, 62%. These results suggest that Controne bean PE may be of interest for potential nutraceutical applications. |
Databáze: | OpenAIRE |
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