Plasma antioxidant defense in actinic keratosis and basal cell carcinoma
| Autor: | Pervin Vural, Dilek Selçuki, Mukaddes Canbaz |
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| Rok vydání: | 1999 |
| Předmět: |
Adult
Male medicine.medical_specialty Antioxidant Erythrocytes Skin Neoplasms medicine.medical_treatment Dermatology Ascorbic Acid Antioxidants Lipid peroxidation chemistry.chemical_compound Reference Values Internal medicine medicine Humans Vitamin E Basal cell carcinoma Sulfhydryl Compounds Serum Albumin Aged chemistry.chemical_classification Reactive oxygen species integumentary system biology business.industry Albumin Ceruloplasmin Glutathione Keratosis Middle Aged medicine.disease Ascorbic acid Uric Acid Infectious Diseases Endocrinology chemistry Biochemistry Carcinoma Basal Cell biology.protein Female business |
| Zdroj: | Journal of the European Academy of Dermatology and Venereology : JEADV. 13(2) |
| ISSN: | 0926-9959 |
| Popis: | Background Reactive oxygen species and lipid peroxides have been implicated in the pathogenesis of a variety of diseases, particularly cancer. There may be an inverse correlation between lipid peroxidation and antioxidant defense mechanisms. The aim of this study was to investigate whether certain plasma antioxidants (ascorbic acid, α-tocopherol, total thiol groups, ceruloplasmin, urate, albumin and erythrocyte glutathione) are altered in actinic keratosis (AK) and basal cell carcinoma (BCC). Methods Plasma samples and red blood cells (RBC) of 13 patients with AK, 12 with BCC and 16 healthy controls were investigated. Results Data analysis indicates significant decrease of ascorbic acid (P |
| Databáze: | OpenAIRE |
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