Two-Year Clinical Outcomes According to Pre-PCI TIMI Flow Grade and Reperfusion Timing in Non-STEMI After Newer-Generation Drug-Eluting Stents Implantation
| Autor: | Byeong Keuk Kim, Myung Ho Jeong, Chul Min Ahn, Sung Jin Hong, Jung Sun Kim, Yong Hoon Kim, Donghoon Choi, Myeong Ki Hong, Young Guk Ko, Seunghwan Kim, Yangsoo Jang, Ae Young Her |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment 030204 cardiovascular system & hematology 03 medical and health sciences Percutaneous Coronary Intervention 0302 clinical medicine Non stemi Internal medicine medicine Humans In patient cardiovascular diseases 030212 general & internal medicine Myocardial infarction business.industry Mortality rate Percutaneous coronary intervention Drug-Eluting Stents Thrombolysis medicine.disease Treatment Outcome surgical procedures operative Reperfusion Conventional PCI Cardiology ST Elevation Myocardial Infarction Cardiology and Cardiovascular Medicine business therapeutics TIMI |
| Zdroj: | Angiology. 73:152-164 |
| ISSN: | 1940-1574 0003-3197 |
| DOI: | 10.1177/00033197211012537 |
| Popis: | The 2-year clinical outcomes according to pre-percutaneous coronary intervention (PCI) thrombolysis in myocardial infarction (TIMI) flow grade and reperfusion timing were investigated in patients with non-ST-segment elevation myocardial infarction (NSTEMI) who received newer-generation drug-eluting stents. A total of 7506 NSTEMI patients were divided into 2 groups: early (PCI ≤ 24 hours: n = 6398; pre-PCI TIMI 0/1 [n = 2729], pre-PCI TIMI 2/3 [n = 3669]) and delayed (PCI > 24 hours: n = 1108; pre-PCI TIMI 0/1 [n = 428], pre-PCI TIMI 2/3 [n = 680]) invasive groups. Major adverse cardiac events were defined as all-cause death, recurrent myocardial infarction, or any repeat revascularization. All-cause death ( P = 0.005 and 0.009, respectively) and cardiac death ( P = .003 and 0.046, respectively) were significantly higher in pre-PCI TIMI 0/1 patients than in pre-PCI TIMI 2/3 patients both in the early and delayed invasive groups. In pre-PCI TIMI 0/1 patients, all-cause death rate was significantly higher in the delayed group ( P = .023). In pre-PCI TIMI 2/3 patients, the clinical end point was similar between the 2 groups. An early invasive strategy is preferred to a delayed invasive strategy in reducing all-cause death in patients with pre-PCI TIMI 0/1. However, in patients with pre-PCI TIMI 2/3, both treatment strategies are acceptable. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|