A novel Arthrobacter beta-galactosidase with homology to eucaryotic beta-galactosidases
Autor: | K Wang, Jean E. Brenchley, Kevin R. Gutshall |
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Rok vydání: | 1997 |
Předmět: |
Xanthomonas
Protein subunit Molecular Sequence Data Microbiology Homology (biology) Mice Arthrobacter Animals Humans Beta-galactosidase Amino Acid Sequence Molecular Biology Gene Peptide sequence Phylogeny chemistry.chemical_classification biology Phylogenetic tree Base Sequence Sequence Homology Amino Acid Plants biology.organism_classification beta-Galactosidase Molecular biology Enzyme chemistry Biochemistry biology.protein Lysosomes Research Article |
Zdroj: | Journal of bacteriology. 179(9) |
ISSN: | 0021-9193 |
Popis: | An Arthrobacter beta-galactosidase has homology with the lysosomal acid beta-galactosidases from humans and mice and with a Xanthomonas manihotis enzyme. Phylogenetic analysis of the deduced amino acid sequence showed an unusual pattern, with this procaryotic enzyme clustering within the animal clade. The gene encodes a subunit of 52 kDa, and the enzyme appears to be active as a dimer. The enzyme hydrolyzed substrates with either a beta-1,4 or a beta-1,3 linkage. |
Databáze: | OpenAIRE |
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