A novel Arthrobacter beta-galactosidase with homology to eucaryotic beta-galactosidases

Autor: K Wang, Jean E. Brenchley, Kevin R. Gutshall
Rok vydání: 1997
Předmět:
Zdroj: Journal of bacteriology. 179(9)
ISSN: 0021-9193
Popis: An Arthrobacter beta-galactosidase has homology with the lysosomal acid beta-galactosidases from humans and mice and with a Xanthomonas manihotis enzyme. Phylogenetic analysis of the deduced amino acid sequence showed an unusual pattern, with this procaryotic enzyme clustering within the animal clade. The gene encodes a subunit of 52 kDa, and the enzyme appears to be active as a dimer. The enzyme hydrolyzed substrates with either a beta-1,4 or a beta-1,3 linkage.
Databáze: OpenAIRE