Supplementary Figures S1-S7 from Single-Cell Analysis Reveals a Preexisting Drug-Resistant Subpopulation in the Luminal Breast Cancer Subtype

Autor: Yusuke Yamamoto, Takahiro Ochiya, Hideo Sasaki, Iwao Shimomura, Ryou-u Takahashi, Wataru Usuba, Marta Prieto-Vila
Rok vydání: 2023
DOI: 10.1158/0008-5472.22421097
Popis: Figure S1. Schematic representation of workflow for single-cell isolation and sc-qPCR. Figure S2. Violin plot of each individual gene expression along drug resistance acquisition. Figure S3. Correlation of several genes expressed at the single-cell level, separated by cell type as represented by the color of each dot. Figure S4. Lef1, Vim and Cav1 protein expression in several Luminal breast cancer cell lines. Figure S5. Larger visual fields showing immunostaining in tissue samples. Figure S6. Clinical information regarding the role of Lef1 in stained tissue samples. Figure S7. Comparison of Lef1 protein levels in MCF7 and derivatives.
Databáze: OpenAIRE