Exposure measurement of aflatoxins and aflatoxin metabolites in human body fluids. A short review
| Autor: | Aishah A. Latiff, Nurul Izzah Ahmad, A. Rosma, Yin-Hui Leong |
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| Rok vydání: | 2012 |
| Předmět: |
Aflatoxin
Food Contamination Aspergillus flavus Urine Breast milk Toxicology Microbiology Eating Aflatoxins Humans Ingestion heterocyclic compounds Food science Exposure measurement biology Chemistry technology industry and agriculture food and beverages biology.organism_classification biological factors Body Fluids Biomarker (medicine) Biomarkers Biotechnology Food contaminant |
| Zdroj: | Mycotoxin Research. 28:79-87 |
| ISSN: | 1867-1632 0178-7888 |
| DOI: | 10.1007/s12550-012-0129-8 |
| Popis: | Aflatoxins are highly toxic secondary fungal metabolites mainly produced by Aspergillus flavus and A. parasiticus. Human exposure to aflatoxins may result directly from ingestion of contaminated foods, or indirectly from consumption of foods from animals previously exposed to aflatoxins in feeds. This paper focuses on exposure measurement of aflatoxins and aflatoxin metabolites in various human body fluids. Research on different metabolites present in blood, urine, breast milk, and other human fluids or tissues including their detection techniques is reviewed. The association between dietary intake of aflatoxins and biomarker measurement is also highlighted. Finally, aspects related to the differences between aflatoxin determination in food versus the biomarker approach are discussed. |
| Databáze: | OpenAIRE |
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