Joint American Academy of Dermatology–National Psoriasis Foundation guidelines of care for the management of psoriasis with systemic nonbiologic therapies

Autor: Dario Kivelevitch, Jason Lichten, April W. Armstrong, Robert S. Rahimi, Emily B. Wong, Reena N. Rupani, Nehal N. Mehta, Alan Menter, Neil J. Korman, Craig A. Elmets, Amy S. Paller, Arun L. Pathy, Craig L. Leonardi, Arthur Kavanaugh, Boni E. Elewski, Matthew Kiselica, Daniel H. Kaplan, Sylvia L. Parra, Michael Siegel, Benjamin K. Stoff, Dawn Marie R. Davis, Mark Lebwohl, Kenneth B. Gordon, Alice B. Gottlieb, Cody Connor, Jashin J. Wu, Bruce Strober, Kelly M. Cordoro, Elizabeth Farley Prater, Elliot B. Tapper, Vidhya Hariharan, Henry W. Lim, Daniela Kroshinsky, Joel M. Gelfand
Rok vydání: 2020
Předmět:
Zdroj: Journal of the American Academy of Dermatology. 82:1445-1486
ISSN: 0190-9622
Popis: Psoriasis is a chronic inflammatory disease involving multiple organ systems and affecting approximately 2% of the world's population. In this guideline, we focus the discussion on systemic, nonbiologic medications for the treatment of this disease. We provide detailed discussion of efficacy and safety for the most commonly used medications, including methotrexate, cyclosporine, and acitretin, and provide recommendations to assist prescribers in initiating and managing patients on these treatments. Additionally, we discuss newer therapies, including tofacitinib and apremilast, and briefly touch on a number of other medications, including fumaric acid esters (used outside the United States) and therapies that are no longer widely used for the treatment of psoriasis (ie, hydroxyurea, leflunomide, mycophenolate mofetil, thioguanine, and tacrolimus).
Databáze: OpenAIRE