Spontaneous mesenteric hematoma of the sigmoid colon associated with rivaroxaban: A case report

Autor: Tadashi Bando, Tsutomu Fujii, Tetsuro Shimizu, Tomoyuki Okumura, Soshi Osawa, Katsuhisa Hirano
Rok vydání: 2018
Předmět:
medicine.medical_specialty
Abdominal pain
medicine.medical_treatment
SRA
superior rectal artery

030204 cardiovascular system & hematology
Article
Anticoagulation
03 medical and health sciences
0302 clinical medicine
Hematoma
Rivaroxaban
Melena
PT
prothrombin time

medicine
cardiovascular diseases
Mesenteric hematoma
Sigmoid colon
Mesentery
APTT
activated partial thromboplastin time

DOAC
direct oral anticoagulant

business.industry
Colostomy
pathological conditions
signs and symptoms

LCA
left colic artery

medicine.disease
CT
computed tomography

Surgery
body regions
surgical procedures
operative

medicine.anatomical_structure
cardiovascular system
Abdomen
030211 gastroenterology & hepatology
IVR
interventional radiography

PT-INR
prothrombin time-international normalized ratio

medicine.symptom
business
medicine.drug
Zdroj: International Journal of Surgery Case Reports
ISSN: 2210-2612
DOI: 10.1016/j.ijscr.2018.02.008
Popis: Highlights • Mesenteric hematoma is a rare condition without specific symptoms. • Rivaroxaban is not affect to the value of PT or APTT. • It is difficult to diagnose mesenteric hematoma.
Introduction Mesenteric hematoma is a rare condition caused by bleeding localized in the mesenteric vascular tree. This is a first report of spontaneous mesenteric hematoma caused by rivaroxaban. Presentation of case The patient was a 71-year-old man who had taken rivaroxaban for paroxysmal atrial fibrillation. He had experienced abdominal pain and diarrhea for the prior 3 days. He had little melena and was referred to our institute. He presented with hypotension on arrival. Computed tomography (CT) revealed a 10 cm mass in the mesentery of the sigmoid colon with extravasation. Active bleeding from the sigmoid colic arteries was embolized with angiography on the day of admission. On the second day, we operated on the patient. We detected 200 mL of bloody ascites accumulated in the abdomen. The serosa of the sigmoid colon was ruptured along the tenia due to the compression of the hematoma in the mesentery. The sigmoid colon was resected and a descending colostomy was reconstructed. Operative and pathological findings did not reveal the cause of bleeding. We finally diagnosed the patient with spontaneous mesenteric hematoma associated with rivaroxaban. Discussion Previous reports of mesenteric hematoma with anticoagulant were associated with warfarin. Since rivaroxaban is not affect to the value of prothrombin time (PT) and activated partial thromboplastin time (APTT) and mesenteric hematoma presents non-specific symptoms, it is difficult to diagnose mesenteric hematoma in the patients taking rivaroxaban. Conclusion It is important to keep in mind that mesenteric hematoma is one of the critical complications in patients taking rivaroxaban.
Databáze: OpenAIRE