Adrenal incidentaloma: the influence of a decision-making algorithm on the short-term outcome of laparoscopy
| Autor: | Borrelli A, Pietro Tonelli, Giuseppe Manca, Alessandro Peri, Massimo Mannelli, Carlo Bergamini, L. Presenti, Andrea Valeri |
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| Rok vydání: | 2005 |
| Předmět: |
Laparoscopic surgery
Adult Male medicine.medical_specialty medicine.medical_treatment Adrenal Gland Neoplasms Decision Support Techniques Adrenal masses Blood loss medicine Delayed surgery Humans Adrenal incidentaloma Laparoscopy Aged Incidental Findings medicine.diagnostic_test business.industry Middle Aged Outcome parameter Surgery Operative time Female business Algorithm Algorithms |
| Zdroj: | Journal of laparoendoscopicadvanced surgical techniques. Part A. 15(5) |
| ISSN: | 1092-6429 |
| Popis: | At the present time, the precise indications for laparoscopic surgery of adrenal incidentaloma (AI) have yet to be completely clarified. The most controversial issue is the role of laparoscopy in the treatment of potentially malignant and large adrenal masses. Trying to address these questions, we retrospectively examined a group of patients with AIs.Forty-two patients with AIs who were laparoscopically treated since 1995 were enrolled in this study. The patients were divided into two groups: the 27 patients of the immediate surgery (IS) group were operated on immediately, whereas the 15 subjects in the delayed surgery (DS) group needed further evaluations and/or a follow-up period before surgery. Surgical timing for both groups was decided according to a widely accepted decision-making algorithm. Many outcome parameters of laparoscopy (operative time, blood loss, conversion rate, time to liquid and solid food nutrition, drainage removal, resumption of normal bowel habits, and average hospital stay) were analyzed in the two groups. The subjects had AIs of various sizes and different histotypes.Patients in the DS group had a higher risk for malignancy. The definitive pathology revealed a malignant biology in 26.6% of DS vs. 0% of IS cases. No difference in the outcome parameters of laparoscopy was observed between the two groups or among pathologically different AIs. A significant correlation was found between the operative time and the size of the AI (r=0.836, P0.001, linear regression test).Our study shows that laparoscopy is feasible and safe for AIs, regardless of the preoperative probability of malignancy. The size of the AI was the only determinant for choosing a laparotomy. Further long-term studies are necessary to confirm the laparoscopic efficacy in terms of oncologic safety. |
| Databáze: | OpenAIRE |
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