Biological monitoring of pyrethroids in blood and pyrethroid metabolites in urine: applications and limitations
| Autor: | Karl-Heinz Kühn, Helga Idel, G. Leng |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
Male Insecticides Environmental Engineering Chromatography Gas Formates Metabolite Urine Cyfluthrin Benzoates Gas Chromatography-Mass Spectrometry Hemostatics Cypermethrin chemistry.chemical_compound Occupational Exposure parasitic diseases Nitriles Pyrethrins medicine Environmental Chemistry Humans Waste Management and Disposal Permethrin Chromatography Pyrethroid Stereoisomerism Pesticide Middle Aged Pollution chemistry Female Pest Control Gas chromatography–mass spectrometry Blood Chemical Analysis medicine.drug Environmental Monitoring Half-Life |
| Zdroj: | The Science of the total environment. 199(1-2) |
| ISSN: | 0048-9697 |
| Popis: | Copyright (c) 1997 Elsevier Science B.V. All rights reserved. The objective of this study was to perform biological monitoring of subjects who are occupationally exposed to pyrethroids. The study group consisted of 30 pest control operators exposed to cyfluthrin, cypermethrin or permethrin. After exposure, 24-h urine samples were collected and 20 ml of blood was drawn. The pyrethroid metabolites cis- and trans-3-(2,2-dichlorovinyl)-2,2-dimethy lcyclopropanecarboxylic acid, 3-phenoxybenzoic acid and fluorophenoxybenzoic acid were determined in the urine samples (limit of detection: 0.5 μg/l) by GC MS and the pyrethroids in plasma (limit of detection: 5 μg/l) by GC-ECD. The concentrations of metabolites in the urine of the pest control operators ranged between |
| Databáze: | OpenAIRE |
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