The Simultaneous Onset of Pancreatitis and Colitis as Immune-related Adverse Events in a Patient Receiving Nivolumab Treatment for Renal Cell Carcinoma
Autor: | Hiroaki Shiina, Akihiko Oka, Naoki Oshima, Shunji Ishihara, Hiroshi Tobita, Yoshiyuki Mishima, Norihisa Ishimura, Taichi Nagami, Riruke Maruyama, Eiko Okimoto, Ichiro Moriyama, Hiroki Sonoyama, Tomotaka Yazaki, Kousaku Kawashima, Kotaro Shibagaki |
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Rok vydání: | 2022 |
Předmět: |
Male
Oncology medicine.medical_specialty Immune checkpoint inhibitors Immune system Renal cell carcinoma Internal medicine Internal Medicine medicine Humans Colitis Adverse effect Carcinoma Renal Cell business.industry General Medicine medicine.disease Kidney Neoplasms Nivolumab Pancreatitis Acute Disease Acute pancreatitis Female business |
Zdroj: | Internal Medicine. 61:1485-1490 |
ISSN: | 1349-7235 0918-2918 |
Popis: | Immune checkpoint inhibitors (ICIs), which have anti-tumor effects, are currently approved for treatment of several kinds of advanced malignancies. However, with their increasing use, a variety of immune-related adverse events (irAEs) in administered patients have been reported. We herein report a rare case of the simultaneous onset of acute pancreatitis and colitis as irAEs during nivolumab treatment given to a patient with renal cell carcinoma, who then shown marked improvement with corticosteroid therapy. |
Databáze: | OpenAIRE |
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