Cord blood levels of corticotropin-releasing factor
| Autor: | Hitosi Yunoki, Hideki Yagi, Takayosi Kuroume, Kanji Nagashima, Takashi Noji |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
Male
endocrine system medicine.medical_specialty Hydrocortisone Corticotropin-Releasing Hormone Radioimmunoassay Dehydroepiandrosterone Umbilical cord chemistry.chemical_compound Dehydroepiandrosterone sulfate Internal medicine medicine Humans Child Fetus business.industry Dehydroepiandrosterone Sulfate Infant Newborn Fetal Blood Fetal circulation Endocrinology medicine.anatomical_structure chemistry Cord blood Pediatrics Perinatology and Child Health Female business hormones hormone substitutes and hormone antagonists Glucocorticoid Developmental Biology medicine.drug |
| Zdroj: | Biology of the neonate. 51(1) |
| ISSN: | 0006-3126 |
| Popis: | The levels of corticotropin-releasing factor (CRF) in the cord blood from 34 infants were determined by radioimmunoassay. All infants were born by vaginal delivery after an uneventful pregnancy. Levels of cortisol, dehydroepiandrosterone sulfate and ACTH were high in the cord blood. CRF levels (mean ± SD) were 100.5 ± 31.7 and 44.5 ± 7.8 pg/ml, respectively, in cord blood and in controls (healthy prepubertal children, n = 10). Although the origin of CRF in peripheral circulation has not been clarified, we speculate that the high adrenocortical steroid synthesis of the fetus might be a consequence of high CRF levels in fetal circulation. |
| Databáze: | OpenAIRE |
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